2017-8-11 16:0:3Tue Feb 02 2016 13:51:57 GMT+0100 (CET)
proteinLength
57
geneLength
171
ec
outlinks
subtilist
gene_detail+BG10753
gene_detail BG10753
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
GP959 (spc), available in [SW|Jörg Stülke]'s lab
DS91 (spc) NCIB3610 derivate, available in [SW|Jörg Stülke]'s lab
1S98 ( ''sinI''::''kan''), [Pubmed|11466285], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S98&Search=1S98 BGSC]
GP1663 (''[[gene|yqhG]]-[[gene|sinI]]-[[gene|sinR]]-[[gene|tasA]]''), available in [SW|Jörg Stülke]'s lab
GP959 (spc), available in [SW|Jörg Stülke]'s lab
DS91 (spc) NCIB3610 derivate, available in [SW|Jörg Stülke]'s lab
1S98 ( ''sinI''::''kan''), [Pubmed|11466285], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S98&Search=1S98 BGSC]
GP1663 (''[[protein|yqhG]]-[[protein|sinI]]-[[protein|sinR]]-[[protein|tasA]]''), available in [SW|Jörg Stülke]'s lab
References
Modelling of the [[protein|SinI]]]/[[SinR] switch
References
Original publications
outlinks
bsupath
sinI_2552446_2552619_1
[SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|transition state regulators], [SW|biofilm formation]
Gene
Coordinates on the chromosome (coding sequence)
2,552,446 -> 2,552,619
The protein
[SW|Interactions]
[[protein|SinR]]-[[protein|SinI]] [Pubmed|9799632], K(D) 1.8 nM [Pubmed|23430750]
Expression and Regulation
Operon
''[[protein|sinI]]-[[protein|sinR]]'' [Pubmed|3125149]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|3125149]
Expression and Regulation
Regulation
activated under conditions that trigger sporulation by ([SW|Spo0A]) interaction [Pubmed|11751836],[Pubmed|21326214]
repressed during exponential growth ([[protein|ScoC]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/1906467,11751836 PubMed]
repressed during logrithmic growth ([[protein|AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7635837,11751836 PubMed]
repressed during vegetative growth ([[protein|SinR]]) [Pubmed|1664536]
Expression and Regulation
Regulatory mechanism
[SW|Spo0A]: transcription activation, in a portion of cells [Pubmed|11751836]
[[protein|ScoC]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/1906467,11751836 PubMed]
[[protein|AbrB]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/7635837,11751836 PubMed]
[[protein|SinR]]: transcription repression [Pubmed|1664536]
Expression and Regulation
Additional information
the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] [PubMed|21815947]
References
Modelling of the [SW|SinI]]/[[SinR] switch