SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:3Tue Feb 02 2016 13:51:57 GMT+0100 (CET)

proteinLength

57

geneLength

171

ec

outlinks

subtilist

gene_detail+BG10753

gene_detail BG10753

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

GP959 (spc), available in [SW|Jörg Stülke]'s lab

DS91 (spc) NCIB3610 derivate, available in [SW|Jörg Stülke]'s lab

1S98 ( ''sinI''::''kan''), [Pubmed|11466285], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S98&Search=1S98 BGSC]

GP1663 (''[[gene|yqhG]]-[[gene|sinI]]-[[gene|sinR]]-[[gene|tasA]]''), available in [SW|Jörg Stülke]'s lab

GP959 (spc), available in [SW|Jörg Stülke]'s lab

DS91 (spc) NCIB3610 derivate, available in [SW|Jörg Stülke]'s lab

1S98 ( ''sinI''::''kan''), [Pubmed|11466285], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S98&Search=1S98 BGSC]

GP1663 (''[[protein|yqhG]]-[[protein|sinI]]-[[protein|sinR]]-[[protein|tasA]]''), available in [SW|Jörg Stülke]'s lab

References

Modelling of the [[protein|SinI]]]/[[SinR] switch

21095906

References

Original publications

23430750, 23012477, 21326214, 21815947, 3125149, 15661000, 18047568, 11751836, 1906467, 11751836, 7635837, 11751836, 10547280, 15104138, 9799632, 20923420, 8422983, 24256735

23430750, 23012477, 21326214, 21815947, 3125149, 15661000, 18047568, 11751836, 1906467, 11751836, 7635837, 11751836, 10547280, 15104138, 9799632, 20923420, 8422983, 24256735, 26819068

outlinks

bsupath

sinI_2552446_2552619_1

[SW|Categories] containing this gene/protein

[SW|transcription factors and their control], [SW|transition state regulators], [SW|biofilm formation]

Gene

Coordinates on the chromosome (coding sequence)

2,552,446 -> 2,552,619

The protein

[SW|Interactions]

[[protein|SinR]]-[[protein|SinI]] [Pubmed|9799632], K(D) 1.8 nM [Pubmed|23430750]

Expression and Regulation

Operon

''[[protein|sinI]]-[[protein|sinR]]'' [Pubmed|3125149]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|3125149]

Expression and Regulation

Regulation

activated under conditions that trigger sporulation by ([SW|Spo0A]) interaction [Pubmed|11751836],[Pubmed|21326214]

repressed during exponential growth ([[protein|ScoC]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/1906467,11751836 PubMed]

repressed during logrithmic growth ([[protein|AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7635837,11751836 PubMed]

repressed during vegetative growth ([[protein|SinR]]) [Pubmed|1664536]

Expression and Regulation

Regulatory mechanism

[SW|Spo0A]: transcription activation, in a portion of cells [Pubmed|11751836]

[[protein|ScoC]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/1906467,11751836 PubMed]

[[protein|AbrB]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/7635837,11751836 PubMed]

[[protein|SinR]]: transcription repression [Pubmed|1664536]

Expression and Regulation

Additional information

the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] [PubMed|21815947]

References

Modelling of the [SW|SinI]]/[[SinR] switch

21095906